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KMID : 0358520090210030246
Korean Journal of Occupational and Environmental Medicine
2009 Volume.21 No. 3 p.246 ~ p.258
A Study on Olfactory Function in Painters Exposed to Organic Solvent in a Shipyard
Min Keong-Bum

Son Jun-Seok
Kim Young-Wook
Chae Chang-Ho
Yi Cheol-Ho
Kim Chan-Woo
Shin Young-Who
Abstract
Objectives: To investigate the effect of the occupational exposure to organic solvent on the olfactory function of shipyard painters; we measured the prevalence of olfactory function impairment between the exposure group and the controls by using the Korean Version of the Sniffin¡¯Stick (KVSS) test through smell, and by analyzing factors related to olfactory alteration.

Methods: The olfactory function of 245 painters exposed to organic solvents was compared to that of 122 unexposed controls. A total of 367 shipyard subjects underwent questionnaire study and the olfactory function test was performed by KVSS test I from April to August 2007. Suspected subjects of abnormal findings were referred to an otorhinolaryngologist. In addition, the Biologic Exposure Index (BEI) and industrial hygiene laboratory data were collected as well as analyzed by job title in the exposure group.

Results: The difference in the result of KVSS test I was significantly different from the exposure group and the controls (P<0.05). For the exposure group, reduced olfaction and exposure group were correlated with statistical significance when compared to the controls (P<0.01). Adjusting for work duration, smoking, rhinitis or sinusitis history, exposure of the organic solvent (OR 1.76, 95% CI=1.05-2.96) had a statistically meaningful relationship with decreased olfaction. The data on BEI for the exposure group were collected; the difference in methylhippuric acid was significant between spray workers and others, but did not correlate well with decreased olfaction.

Conclusion: Occupational exposure to organic solvents in shipyard painters may affect the olfactory function. Therefore, shipyard painters should be monitored on a periodic bases by the quantitative test such as KVSS test. There is no other quantitative testing method or standardized procedure that can objectively diagnose the neurotoxic effect, further enhanced quality research in this field is necessary.
KEYWORD
Occupational exposure, Organic solvent, Smell, Paintings
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